Magnesium Bisglycinate

What Is Magnesium Bisglycinate?

Magnesium Bisglycinate by Thorne delivers elemental magnesium in the bisglycinate chelate form — a highly bioavailable, amino acid-bound magnesium that is exceptionally well tolerated compared to oxide, sulfate, or citrate forms that can cause digestive discomfort. Provided as a powder (187g, 60 servings), it mixes easily into water or a smoothie and is NSF Certified for Sport. Magnesium is an essential mineral involved in over 300 enzymatic reactions in the body, yet deficiency is one of the most common nutritional shortfalls in modern adults due to soil depletion, poor diet, and stress-driven depletion.

Key Benefits

• Supports deep, restful sleep and healthy sleep cycle regulation by promoting muscle and nervous system relaxation
• Promotes muscle relaxation, reduced cramping, and faster post-exercise recovery
• Supports healthy heart rhythm and cardiovascular function as a critical electrolyte for the heart muscle
• Helps maintain healthy energy metabolism through its role in ATP production
• Supports healthy stress response and nervous system calm by modulating the HPA axis
• Bisglycinate chelate form is gentle on the GI tract — no laxative effect at standard doses

Who Should Take This?

Magnesium Bisglycinate is an excellent choice for adults dealing with muscle tension, cramping, or poor sleep quality, athletes and active individuals seeking enhanced recovery, patients under high stress with elevated magnesium depletion, individuals taking medications known to deplete magnesium (certain blood pressure medications, proton pump inhibitors), and anyone seeking a gentle, highly bioavailable magnesium for general wellness. Our doctors consider magnesium one of the most universally beneficial supplements for the musculoskeletal patients we serve.

How to Use

• Serving size: Mix 1 scoop (approximately 3.1g) into 8oz of water or a beverage once daily
• Timing: Best taken in the evening 30–60 minutes before bed to leverage magnesium’s calming and sleep-supportive effects
• Duration: Suitable for ongoing daily use; most patients notice improvements in sleep and muscle tension within 1–2 weeks
• Stacking: Pairs well with L-Theanine or PharmaGABA-250 for a comprehensive sleep and relaxation protocol, and with Curcumin Phytosome and Super EPA for joint and muscle recovery support

Our Doctors’ Take

Our doctors recommend magnesium to a significant portion of our patient base — particularly those dealing with muscle tightness, restless sleep, or stress-driven fatigue. It is one of the most evidence-supported supplements for conditions we see daily in practice. The bisglycinate form is our preferred choice because it avoids the GI side effects (loose stools) that commonly cause patients to discontinue oxide or citrate forms, and the NSF certification reassures our athletes. The powder format is also a practical advantage for patients who struggle with swallowing pills.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.